Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells

Binary enterotoxins Clostridium (C.) botulinum C2 toxin, C. perfringens iota toxin and C. difficile toxin CDT are composed of a transport (B) and a separate non-linked enzyme (A) component. Their B-components mediate endocytic uptake into mammalian cells and subsequently transport of the A-component...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ernst, Katharina, Schmid, Johannes, Beck, Matthias, Hägele, Marlen, Hohwieler, Meike, Hauff, Patricia, Ückert, Anna Katharina, Anastasia, Anna, Fauler, Michael, Jank, Thomas, Aktories, Klaus, Popoff, Michel R., Schiene-Fischer, Cordelia, Kleger, Alexander, Müller, Martin, Frick, Manfred, Barth, Holger
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457432/
https://ncbi.nlm.nih.gov/pubmed/28578412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02882-y
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki