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β-lapachone suppresses tumour progression by inhibiting epithelial-to-mesenchymal transition in NQO1-positive breast cancers

NQO1 is a FAD-binding protein that can form homodimers and reduce quinones to hydroquinones, and a growing body of evidence currently suggests that NQO1 is dramatically elevated in solid cancers. Here, we demonstrated that NQO1 was elevated in breast cancer and that its expression level was positive...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Yang, Yang, Zhou, Xianchun, Xu, Ming, Piao, Junjie, Zhang, Yuan, Lin, Zhenhua, Chen, Liyan
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457413/
https://ncbi.nlm.nih.gov/pubmed/28578385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02937-0
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