β-lapachone suppresses tumour progression by inhibiting epithelial-to-mesenchymal transition in NQO1-positive breast cancers

NQO1 is a FAD-binding protein that can form homodimers and reduce quinones to hydroquinones, and a growing body of evidence currently suggests that NQO1 is dramatically elevated in solid cancers. Here, we demonstrated that NQO1 was elevated in breast cancer and that its expression level was positive...

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Udgivet i:Sci Rep
Main Authors: Yang, Yang, Zhou, Xianchun, Xu, Ming, Piao, Junjie, Zhang, Yuan, Lin, Zhenhua, Chen, Liyan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457413/
https://ncbi.nlm.nih.gov/pubmed/28578385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02937-0
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