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β-lapachone suppresses tumour progression by inhibiting epithelial-to-mesenchymal transition in NQO1-positive breast cancers

NQO1 is a FAD-binding protein that can form homodimers and reduce quinones to hydroquinones, and a growing body of evidence currently suggests that NQO1 is dramatically elevated in solid cancers. Here, we demonstrated that NQO1 was elevated in breast cancer and that its expression level was positive...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Yang, Yang, Zhou, Xianchun, Xu, Ming, Piao, Junjie, Zhang, Yuan, Lin, Zhenhua, Chen, Liyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457413/
https://ncbi.nlm.nih.gov/pubmed/28578385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02937-0
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