Mycobacterium tuberculosis arrests host cycle at the G(1)/S transition to establish long term infection

Signals modulating the production of Mycobacterium tuberculosis (Mtb) virulence factors essential for establishing long-term persistent infection are unknown. The WhiB3 redox regulator is known to regulate the production of Mtb virulence factors, however the mechanisms of this modulation are unknown...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Cumming, Bridgette M., Rahman, Md. Aejazur, Lamprecht, Dirk A., Rohde, Kyle H., Saini, Vikram, Adamson, John H., Russell, David G., Steyn, Adrie J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456404/
https://ncbi.nlm.nih.gov/pubmed/28542477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006389
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