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Pharmacokinetics of caspofungin acetate to guide optimal dosing in cats

Cats are the most common mammal to develop invasive fungal rhinosinusitis caused by cryptic species in Aspergillus section Fumigati that are resistant to azoles but susceptible to caspofungin. In this study nonlinear mixed-effects pharmacokinetic modeling and simulation was used to investigate caspo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Leshinsky, Jana, McLachlan, Andrew, Foster, David J. R., Norris, Ross, Barrs, Vanessa R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456383/
https://ncbi.nlm.nih.gov/pubmed/28575121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178783
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