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Terbinafine in Combination with Other Antifungal Agents for Treatment of Resistant or Refractory Mycoses: Investigating Optimal Dosing Regimens Using a Physiologically Based Pharmacokinetic Model

Terbinafine is increasingly used in combination with other antifungal agents to treat resistant or refractory mycoses due to synergistic in vitro antifungal activity; high doses are commonly used, but limited data are available on systemic exposure, and no assessment of pharmacodynamic target attain...

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Bibliografische gegevens
Hoofdauteurs: Dolton, Michael J., Perera, Vidya, Pont, Lisa G., McLachlan, Andrew J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910715/
https://ncbi.nlm.nih.gov/pubmed/24126579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02006-13
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