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Physiologically Based Pharmacokinetic Model for Terbinafine in Rats and Humans
The aim of this study was to develop a physiologically based pharmacokinetic (PB-PK) model capable of describing and predicting terbinafine concentrations in plasma and tissues in rats and humans. A PB-PK model consisting of 12 tissue and 2 blood compartments was developed using concentration-time d...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127287/ https://ncbi.nlm.nih.gov/pubmed/12069977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.7.2219-2228.2002 |
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