Physiologically Based Pharmacokinetic Model for Terbinafine in Rats and Humans

The aim of this study was to develop a physiologically based pharmacokinetic (PB-PK) model capable of describing and predicting terbinafine concentrations in plasma and tissues in rats and humans. A PB-PK model consisting of 12 tissue and 2 blood compartments was developed using concentration-time d...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Hosseini-Yeganeh, Mahboubeh, McLachlan, Andrew J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Pharmacology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12069977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.7.2219-2228.2002
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