Physiologically Based Pharmacokinetic Model for Terbinafine in Rats and Humans
The aim of this study was to develop a physiologically based pharmacokinetic (PB-PK) model capable of describing and predicting terbinafine concentrations in plasma and tissues in rats and humans. A PB-PK model consisting of 12 tissue and 2 blood compartments was developed using concentration-time d...
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| Опубликовано в:: | Antimicrob Agents Chemother |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12069977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.7.2219-2228.2002 |
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