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SOS-Independent Induction of dinB Transcription by β-Lactam-Mediated Inhibition of Cell Wall Synthesis in Escherichia coli

Transcription of the dinB gene, encoding DNA polymerase IV, is induced by the inhibition of cell wall synthesis at different levels. Using the β-lactam antibiotic ceftazidime, a PBP3 inhibitor, as a model, we have shown that this induction is independent of the LexA/RecA regulatory system. Induction...

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Autors principals: Pérez-Capilla, Tatiana, Baquero, María-Rosario, Gómez-Gómez, José-María, Ionel, Alina, Martín, Soledad, Blázquez, Jesús
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC545630/
https://ncbi.nlm.nih.gov/pubmed/15687217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.4.1515-1518.2005
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