Single-Strand-Specific Exonucleases Prevent Frameshift Mutagenesis by Suppressing SOS Induction and the Action of DinB/DNA Polymerase IV in Growing Cells

Escherichia coli strains carrying null alleles of genes encoding single-strand-specific exonucleases ExoI and ExoVII display elevated frameshift mutation rates but not base substitution mutation rates. We characterized increased spontaneous frameshift mutation in ExoI(−) ExoVII(−) cells and report t...

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Bibliographic Details
Main Authors: Hersh, Megan N., Morales, Liza D., Ross, Kimberly J., Rosenberg, Susan M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1428391/
https://ncbi.nlm.nih.gov/pubmed/16547019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.7.2336-2342.2006
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