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Role of Cigarette Smoke–Induced Aggresome Formation in Chronic Obstructive Pulmonary Disease–Emphysema Pathogenesis

Cigarette smoke (CS) exposure is known to induce proteostasis imbalance that can initiate accumulation of ubiquitinated proteins. Therefore, the primary goal of this study was to determine if first- and secondhand CS induces localization of ubiquitinated proteins in perinuclear spaces as aggresome b...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Tran, Ian, Ji, Changhoon, Ni, Inzer, Min, Taehong, Tang, Danni, Vij, Neeraj
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455694/
https://ncbi.nlm.nih.gov/pubmed/25490051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0107OC
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