Impact of Diabetes, Insulin, and Metformin Use on the Outcome of Patients With Human Epidermal Growth Factor Receptor 2–Positive Primary Breast Cancer: Analysis From the ALTTO Phase III Randomized Trial

PURPOSE: Previous studies have suggested an association between metformin use and improved outcome in patients with diabetes and breast cancer. In the current study, we aimed to explore this association in human epidermal growth factor receptor 2 (HER2 ) –positive primary breast cancer in the contex...

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Pubblicato in:J Clin Oncol
Autori principali: Sonnenblick, Amir, Agbor-Tarh, Dominique, Bradbury, Ian, Di Cosimo, Serena, Azim, Hatem A., Fumagalli, Debora, Sarp, Severine, Wolff, Antonio C., Andersson, Michael, Kroep, Judith, Cufer, Tanja, Simon, Sergio D., Salman, Pamela, Toi, Masakazu, Harris, Lyndsay, Gralow, Julie, Keane, Maccon, Moreno-Aspitia, Alvaro, Piccart-Gebhart, Martine, de Azambuja, Evandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2017
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ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455460/
https://ncbi.nlm.nih.gov/pubmed/28375706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.69.7722
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