Pattern of Rash, Diarrhea, and Hepatic Toxicities Secondary to Lapatinib and Their Association With Age and Response to Neoadjuvant Therapy: Analysis From the NeoALTTO Trial

PURPOSE: We investigated the pattern of rash, diarrhea, and hepatic adverse events (AEs) secondary to lapatinib and their association with age and pathologic complete response (pCR) in the Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation (NeoALLTO) phase III trial. PATIENTS AND METHOD...

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Publicado en:J Clin Oncol
Autores principales: Azim, Hatem A., Agbor-tarh, Dominique, Bradbury, Ian, Dinh, Phuong, Baselga, Jose, Di Cosimo, Serena, Greger, James G., Smith, Ian, Jackisch, Christian, Kim, Sung-Bae, Aktas, Bahriye, Huang, Chiun-Sheng, Vuylsteke, Peter, Hsieh, Ruey Kuen, Dreosti, Lydia, Eidtmann, Holger, Piccart, Martine, de Azambuja, Evandro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795667/
https://ncbi.nlm.nih.gov/pubmed/24248687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.50.9448
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