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Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants
Defects in meiotic recombination in many organisms result in arrest because of activation of a meiotic checkpoint(s). The proximal defect that triggers this checkpoint in mammalian germ cells is not understood, but it has been suggested to involve either the presence of DNA damage in the form of unr...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2005
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545532/ https://ncbi.nlm.nih.gov/pubmed/15640358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406212102 |
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