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Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo
The role of endothelium-derived nitric oxide (NO) in acute inflammation is not known. Here, we examine acute inflammation in congenic endothelial NO synthase-deficient (eNOS(-/-)) mice. Intraplantar injection of carrageenan induces a biphasic inflammatory response. The early phase (0-6 h) is largely...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545512/ https://ncbi.nlm.nih.gov/pubmed/15640348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408906102 |
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