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Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line

BACKGROUND: Placental multidrug resistance-associated protein 2 (MRP2), encoded by ABCC2 gene in human, plays a significant role in regulating drugs’ transplacental transfer rates. Studies on placental MRP2 regulation could provide more therapeutic targets for individualized and safe pharmacotherapy...

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Detalhes bibliográficos
Publicado no:Chin Med J (Engl)
Main Authors: Duan, Hong-Yu, Ma, Dan, Zhou, Kai-Yu, Wang, Tao, Zhang, Yi, Li, Yi-Fei, Wu, Jin-Lin, Hua, Yi-Min, Wang, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455046/
https://ncbi.nlm.nih.gov/pubmed/28524836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.206352
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