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Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis

Drug-induced liver injury (DILI) can broadly be divided into predictable and dose dependent such as acetaminophen (APAP) and unpredictable or idiosyncratic DILI (IDILI). Liver injury from drug hepatotoxicity (whether idiosyncratic or predictable) results in hepatocyte cell death and inflammation. Th...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Iorga, Andrea, Dara, Lily, Kaplowitz, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454931/
https://ncbi.nlm.nih.gov/pubmed/28486401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051018
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