Dicarbonyls and Advanced Glycation End-Products in the Development of Diabetic Complications and Targets for Intervention

Advanced glycation end-products (AGEs) are non-enzymatic protein and amino acid adducts as well as DNA adducts which form from dicarbonyls and glucose. AGE formation is enhanced in diabetes and is associated with the development of diabetic complications. In the current review, we discuss mechanisms...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Brings, Sebastian, Fleming, Thomas, Freichel, Marc, Muckenthaler, Martina U., Herzig, Stephan, Nawroth, Peter P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454897/
https://ncbi.nlm.nih.gov/pubmed/28475116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050984
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