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Dicarbonyls and Advanced Glycation End-Products in the Development of Diabetic Complications and Targets for Intervention

Advanced glycation end-products (AGEs) are non-enzymatic protein and amino acid adducts as well as DNA adducts which form from dicarbonyls and glucose. AGE formation is enhanced in diabetes and is associated with the development of diabetic complications. In the current review, we discuss mechanisms...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Brings, Sebastian, Fleming, Thomas, Freichel, Marc, Muckenthaler, Martina U., Herzig, Stephan, Nawroth, Peter P.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454897/
https://ncbi.nlm.nih.gov/pubmed/28475116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050984
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