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Dicarbonyls and Advanced Glycation End-Products in the Development of Diabetic Complications and Targets for Intervention
Advanced glycation end-products (AGEs) are non-enzymatic protein and amino acid adducts as well as DNA adducts which form from dicarbonyls and glucose. AGE formation is enhanced in diabetes and is associated with the development of diabetic complications. In the current review, we discuss mechanisms...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454897/ https://ncbi.nlm.nih.gov/pubmed/28475116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050984 |
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