Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER(+) Breast Cancer Cells

Tumor angiogenesis is one of the major hallmarks of tumor progression. Nobiletin is a natural flavonoid isolated from citrus peel that has anti-angiogenic activity. Steroid receptor coactivator (Src) is an intracellular tyrosine kinase so that focal adhesion kinase (FAK) binds to Src to play a role...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sp, Nipin, Kang, Dong Young, Joung, Youn Hee, Park, Jong Hwan, Kim, Wan Seop, Lee, Hak Kyo, Song, Ki-Duk, Park, Yeong-Min, Yang, Young Mok
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454848/
https://ncbi.nlm.nih.gov/pubmed/28468300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050935
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