Methylsulfonylmethane Inhibits RANKL-Induced Osteoclastogenesis in BMMs by Suppressing NF-κB and STAT3 Activities

Osteoclast differentiation is dependent on the activities of receptor activator NF-kB ligand (RANKL) and macrophage colony-stimulating factor (M-CSF). Given that RANKL plays a critical role in osteoclast formation and bone resorption, any new compounds found to alter its activity would be predicted...

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Vydáno v:PLoS One
Hlavní autoři: Joung, Youn Hee, Darvin, Pramod, Kang, Dong Young, SP, Nipin, Byun, Hyo Joo, Lee, Chi-Ho, Lee, Hak Kyo, Yang, Young Mok
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957779/
https://ncbi.nlm.nih.gov/pubmed/27447722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159891
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