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Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei

KU is a heterodimer, consisting of ∼70 and ∼80 kDa subunits (KU70 and KU80, respectively), which is involved in a variety of nuclear functions. We generated tbKU80-deficient trypanosomes to explore the potential role of the tbKU complex in telomere maintenance and transcriptional regulation of varia...

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Detalhes bibliográficos
Main Authors: Janzen, Christian J., Lander, Fabian, Dreesen, Oliver, Cross, George A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545459/
https://ncbi.nlm.nih.gov/pubmed/15602000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh991
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