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Telomerase-Independent Stabilization of Short Telomeres in Trypanosoma brucei

In cancer cells and germ cells, shortening of chromosome ends is prevented by telomerase. Telomerase-deficient cells have a replicative life span, after which they enter senescence. Senescent cells can give rise to survivors that maintain chromosome ends through recombination-based amplification of...

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Auteurs principaux: Dreesen, Oliver, Cross, George A. M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489180/
https://ncbi.nlm.nih.gov/pubmed/16782879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00212-06
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