microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression

Acquisition of resistance to anti-cancer drugs is a significant obstacle to effective cancer treatment. Although several efforts have been made to overcome drug resistance in cancer cells, the detailed mechanisms have not been fully elucidated. Here, we investigated whether microRNAs (miRNAs) functi...

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Publicat a:Exp Mol Med
Autors principals: Lee, Heejin, Kim, Chongtae, Kang, Hoin, Tak, Hyosun, Ahn, Sojin, Yoon, Sungjoo Kim, Kuh, Hyo-Jeong, Kim, Wook, Lee, Eun Kyung
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454440/
https://ncbi.nlm.nih.gov/pubmed/28496200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.33
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