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microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression

Acquisition of resistance to anti-cancer drugs is a significant obstacle to effective cancer treatment. Although several efforts have been made to overcome drug resistance in cancer cells, the detailed mechanisms have not been fully elucidated. Here, we investigated whether microRNAs (miRNAs) functi...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Lee, Heejin, Kim, Chongtae, Kang, Hoin, Tak, Hyosun, Ahn, Sojin, Yoon, Sungjoo Kim, Kuh, Hyo-Jeong, Kim, Wook, Lee, Eun Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454440/
https://ncbi.nlm.nih.gov/pubmed/28496200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.33
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