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microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression

Acquisition of resistance to anti-cancer drugs is a significant obstacle to effective cancer treatment. Although several efforts have been made to overcome drug resistance in cancer cells, the detailed mechanisms have not been fully elucidated. Here, we investigated whether microRNAs (miRNAs) functi...

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Bibliografski detalji
Izdano u:Exp Mol Med
Glavni autori: Lee, Heejin, Kim, Chongtae, Kang, Hoin, Tak, Hyosun, Ahn, Sojin, Yoon, Sungjoo Kim, Kuh, Hyo-Jeong, Kim, Wook, Lee, Eun Kyung
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454440/
https://ncbi.nlm.nih.gov/pubmed/28496200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.33
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