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Modulation of TMEM16A channel activity by the von Willebrand factor type A (VWA) domain of the calcium-activated chloride channel regulator 1 (CLCA1)

Calcium-activated chloride channels (CaCCs) are key players in transepithelial ion transport and fluid secretion, smooth muscle constriction, neuronal excitability, and cell proliferation. The CaCC regulator 1 (CLCA1) modulates the activity of the CaCC TMEM16A/Anoctamin 1 (ANO1) by directly engaging...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sala-Rabanal, Monica, Yurtsever, Zeynep, Berry, Kayla N., Nichols, Colin G., Brett, Tom J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454099/
https://ncbi.nlm.nih.gov/pubmed/28420732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.788232
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