2-Alkylquinolone alkaloid biosynthesis in the medicinal plant Evodia rutaecarpa involves collaboration of two novel type III polyketide synthases

2-Alkylquinolone (2AQ) alkaloids are pharmaceutically and biologically important natural products produced by both bacteria and plants, with a wide range of biological effects, including antibacterial, cytotoxic, anticholinesterase, and quorum-sensing signaling activities. These diverse activities a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Matsui, Takashi, Kodama, Takeshi, Mori, Takahiro, Tadakoshi, Tetsuhiro, Noguchi, Hiroshi, Abe, Ikuro, Morita, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454096/
https://ncbi.nlm.nih.gov/pubmed/28411241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.778977
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