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Use of Patterned Collagen Coated Slides to Study Normal and Scleroderma Lung Fibroblast Migration

Systemic sclerosis (SSc) is a spreading fibrotic disease affecting the skin and internal organs. We aimed to model pathogenic fibroblast migration in SSc in order to identify enhancing factors, measure the effect of migrating cells on underlying extracellular matrix (ECM) and test possible therapeut...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Ahmed Abdi, Bahja, Lopez, Henry, Karrar, Sarah, Renzoni, Elisabetta, Wells, Athol, Tam, Angela, Etomi, Oseme, Hsuan, J. Justin, Martin, George R., Shiwen, Xu, Denton, Christopher P., Abraham, David, Stratton, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453993/
https://ncbi.nlm.nih.gov/pubmed/28572686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02621-3
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