Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease

BACKGROUND: Interstitial lung disease is a major cause of morbidity and mortality in systemic sclerosis (SSc), with insufficiently effective treatment options. Progression of pulmonary fibrosis involves expanding populations of fibroblasts, and the accumulation of extracellular matrix proteins. Char...

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Detalhes bibliográficos
Main Authors: Lindahl, Gisela E, Stock, Carmel JW, Shi-Wen, Xu, Leoni, Patricia, Sestini, Piersante, Howat, Sarah L, Bou-Gharios, George, Nicholson, Andrew G, Denton, Christopher P, Grutters, Jan C, Maher, Toby M, Wells, Athol U, Abraham, David J, Renzoni, Elisabetta A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750263/
https://ncbi.nlm.nih.gov/pubmed/23915349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-80
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