A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis

In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of disabling symptoms. Myocardin Related Transcrip...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Shiwen, Xu, Stratton, Richard, Nikitorowicz-Buniak, Joanna, Ahmed-Abdi, Bahja, Ponticos, Markella, Denton, Christopher, Abraham, David, Takahashi, Ayuko, Suki, Bela, Layne, Matthew D., Lafyatis, Robert, Smith, Barbara D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425676/
https://ncbi.nlm.nih.gov/pubmed/25955164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126015
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