A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis

In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of disabling symptoms. Myocardin Related Transcrip...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Shiwen, Xu, Stratton, Richard, Nikitorowicz-Buniak, Joanna, Ahmed-Abdi, Bahja, Ponticos, Markella, Denton, Christopher, Abraham, David, Takahashi, Ayuko, Suki, Bela, Layne, Matthew D., Lafyatis, Robert, Smith, Barbara D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425676/
https://ncbi.nlm.nih.gov/pubmed/25955164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126015
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