A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis

In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of disabling symptoms. Myocardin Related Transcrip...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Shiwen, Xu, Stratton, Richard, Nikitorowicz-Buniak, Joanna, Ahmed-Abdi, Bahja, Ponticos, Markella, Denton, Christopher, Abraham, David, Takahashi, Ayuko, Suki, Bela, Layne, Matthew D., Lafyatis, Robert, Smith, Barbara D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425676/
https://ncbi.nlm.nih.gov/pubmed/25955164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126015
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