Diacylglycerol Kinase alpha is Involved in the Vitamin E-Induced Amelioration of Diabetic Nephropathy in Mice

Diabetic nephropathy (DN) is one of vascular complications of diabetes and is caused by abnormal protein kinase C activation as a result of increased diacylglycerol (DG) production in diabetic hyperglycaemia. Diacylglycerol kinase (DGK) converts DG into phosphatidic acid. Therefore, it is expected t...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hayashi, Daiki, Yagi, Keiko, Song, Chihong, Ueda, Shuji, Yamanoue, Minoru, Topham, Matthew, Suzaki, Toshinobu, Saito, Naoaki, Emoto, Noriaki, Shirai, Yasuhito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453949/
https://ncbi.nlm.nih.gov/pubmed/28572624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02354-3
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