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Diacylglycerol kinase as a possible therapeutic target for neuronal diseases

Diacylglycerol kinase (DGK) is a lipid kinase converting diacylglycerol to phosphatidic acid, and regulates many enzymes including protein kinase C, phosphatidylinositol 4-phosphate 5-kinase, and mTOR. To date, ten mammalian DGK subtypes have been cloned and divided into five groups, and they show s...

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Bibliografiske detaljer
Main Authors: Shirai, Yasuhito, Saito, Naoaki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005014/
https://ncbi.nlm.nih.gov/pubmed/24708409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-28
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