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Mutational and computational evidence that a nickel-transfer tunnel in UreD is used for activation of Klebsiella aerogenes urease
Nickel-containing urease from Klebsiella aerogenes requires four accessory proteins for proper active site metalation. The metallochaperone UreE delivers nickel to UreG, a GTPase that forms a UreD:UreF:UreG complex which binds to urease apoprotein via UreD. Prior in silico analysis of the homologous...
Shranjeno v:
| izdano v: | Biochemistry |
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| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453724/ https://ncbi.nlm.nih.gov/pubmed/26401965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00942 |
| Oznake: |
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