Circulating FGF19 closely correlates with bile acid synthesis and cholestasis in patients with primary biliary cirrhosis

BACKGROUND AND AIM: Bile acid (BA) synthesis in the liver is regulated by Fibroblast Growth Factor 19 (FGF19) secreted from the ileum as an enterohepatic feedback mechanism. Although FGF19 mRNA is absent in normal liver, FGF19 gene expression was reported to increase in response to both extrahepatic...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Li, Zhanyi, Lin, Bingliang, Lin, Guoli, Wu, Yuankai, Jie, Yusheng, Li, Xiangyong, Ko, Brian, Chong, Yutian, Luo, Jian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453554/
https://ncbi.nlm.nih.gov/pubmed/28570655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178580
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