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Circulating FGF19 closely correlates with bile acid synthesis and cholestasis in patients with primary biliary cirrhosis
BACKGROUND AND AIM: Bile acid (BA) synthesis in the liver is regulated by Fibroblast Growth Factor 19 (FGF19) secreted from the ileum as an enterohepatic feedback mechanism. Although FGF19 mRNA is absent in normal liver, FGF19 gene expression was reported to increase in response to both extrahepatic...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453554/ https://ncbi.nlm.nih.gov/pubmed/28570655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178580 |
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