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Circulating FGF19 closely correlates with bile acid synthesis and cholestasis in patients with primary biliary cirrhosis

BACKGROUND AND AIM: Bile acid (BA) synthesis in the liver is regulated by Fibroblast Growth Factor 19 (FGF19) secreted from the ileum as an enterohepatic feedback mechanism. Although FGF19 mRNA is absent in normal liver, FGF19 gene expression was reported to increase in response to both extrahepatic...

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Publicat a:PLoS One
Autors principals: Li, Zhanyi, Lin, Bingliang, Lin, Guoli, Wu, Yuankai, Jie, Yusheng, Li, Xiangyong, Ko, Brian, Chong, Yutian, Luo, Jian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453554/
https://ncbi.nlm.nih.gov/pubmed/28570655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178580
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