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Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups

Hypoxic-ischemic encephalopathy is a condition caused by reduced oxygen and cerebral blood flow to the brain resulting in neurological impairments. Effective therapeutic treatments to ameliorate these disabilities are still lacking. We sought to investigate the role of sestrin2, a highly conserved s...

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Podrobná bibliografie
Vydáno v:J Cereb Blood Flow Metab
Hlavní autoři: Shi, Xudan, Xu, Liang, Doycheva, Desislava Met, Tang, Jiping, Yan, Min, Zhang, John H
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453464/
https://ncbi.nlm.nih.gov/pubmed/27381825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16656201
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