Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups

Hypoxic-ischemic encephalopathy is a condition caused by reduced oxygen and cerebral blood flow to the brain resulting in neurological impairments. Effective therapeutic treatments to ameliorate these disabilities are still lacking. We sought to investigate the role of sestrin2, a highly conserved s...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Shi, Xudan, Xu, Liang, Doycheva, Desislava Met, Tang, Jiping, Yan, Min, Zhang, John H
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453464/
https://ncbi.nlm.nih.gov/pubmed/27381825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16656201
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