Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups

Hypoxic-ischemic encephalopathy is a condition caused by reduced oxygen and cerebral blood flow to the brain resulting in neurological impairments. Effective therapeutic treatments to ameliorate these disabilities are still lacking. We sought to investigate the role of sestrin2, a highly conserved s...

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Publicado en:J Cereb Blood Flow Metab
Autores principales: Shi, Xudan, Xu, Liang, Doycheva, Desislava Met, Tang, Jiping, Yan, Min, Zhang, John H
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2016
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453464/
https://ncbi.nlm.nih.gov/pubmed/27381825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16656201
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