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Genetics of β-Amyloid Precursor Protein in Alzheimer's Disease
Alzheimer’s disease (AD) is characterized neuropathologically by neuronal cell loss, extracellular neuritic plaques composed of β-amyloid (Aβ), and intracellular neurofibrillary tangles composed of hyperphosphorylated tau protein. Aβ is generated by proteolytic processing of the β-amyloid precursor...
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| Publicado en: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453386/ https://ncbi.nlm.nih.gov/pubmed/28003277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024539 |
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