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The Role of Nuclear Receptor–Binding SET Domain Family Histone Lysine Methyltransferases in Cancer
The nuclear receptor–binding SET Domain (NSD) family of histone H3 lysine 36 methyltransferases is comprised of NSD1, NSD2 (MMSET/WHSC1), and NSD3 (WHSC1L1). These enzymes recognize and catalyze methylation of histone lysine marks to regulate chromatin integrity and gene expression. The growing numb...
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| 發表在: | Cold Spring Harb Perspect Med |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453381/ https://ncbi.nlm.nih.gov/pubmed/28193767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026708 |
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