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The Role of Nuclear Receptor–Binding SET Domain Family Histone Lysine Methyltransferases in Cancer

The nuclear receptor–binding SET Domain (NSD) family of histone H3 lysine 36 methyltransferases is comprised of NSD1, NSD2 (MMSET/WHSC1), and NSD3 (WHSC1L1). These enzymes recognize and catalyze methylation of histone lysine marks to regulate chromatin integrity and gene expression. The growing numb...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Bennett, Richard L., Swaroop, Alok, Troche, Catalina, Licht, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453381/
https://ncbi.nlm.nih.gov/pubmed/28193767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026708
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