MITOCHONDRIA TARGETED SPIN TRAPS: SYNTHESIS, SUPEROXIDE SPIN TRAPPING AND MITOCHONDRIAL UPTAKE

Development of reliable methods and site-specific detection of free radicals is an active area of research. Here, we describe the synthesis and radical-trapping properties of new derivatives of DEPMPO and DIPMPO, bearing mitochondria-targeting triphenylphosphonium cationic moiety or guanidinium cati...

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Publicat a:Chem Res Toxicol
Autors principals: Hardy, Micael, Poulhés, Florent, Rizzato, Egon, Rockenbauer, Antal, Banaszak, Karol, Karoui, Hakim, Lopez, Marcos, Zielonka, Jacek, Vasquez-Vivar, Jeannette, Sethumadhavan, Savitha, Kalyanaraman, Balaraman, Tordo, Paul, Ouari, Olivier
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452977/
https://ncbi.nlm.nih.gov/pubmed/24890552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500032e
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