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The Conjugative Relaxase TrwC Promotes Integration of Foreign DNA in the Human Genome
Bacterial conjugation is a mechanism of horizontal DNA transfer. The relaxase TrwC of the conjugative plasmid R388 cleaves one strand of the transferred DNA at the oriT gene, covalently attaches to it, and leads the single-stranded DNA (ssDNA) into the recipient cell. In addition, TrwC catalyzes sit...
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| Publicado no: | Appl Environ Microbiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452801/ https://ncbi.nlm.nih.gov/pubmed/28411218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00207-17 |
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