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The Conjugative Relaxase TrwC Promotes Integration of Foreign DNA in the Human Genome
Bacterial conjugation is a mechanism of horizontal DNA transfer. The relaxase TrwC of the conjugative plasmid R388 cleaves one strand of the transferred DNA at the oriT gene, covalently attaches to it, and leads the single-stranded DNA (ssDNA) into the recipient cell. In addition, TrwC catalyzes sit...
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| Veröffentlicht in: | Appl Environ Microbiol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452801/ https://ncbi.nlm.nih.gov/pubmed/28411218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00207-17 |
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