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The Conjugative Relaxase TrwC Promotes Integration of Foreign DNA in the Human Genome

Bacterial conjugation is a mechanism of horizontal DNA transfer. The relaxase TrwC of the conjugative plasmid R388 cleaves one strand of the transferred DNA at the oriT gene, covalently attaches to it, and leads the single-stranded DNA (ssDNA) into the recipient cell. In addition, TrwC catalyzes sit...

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Bibliografski detalji
Izdano u:Appl Environ Microbiol
Glavni autori: González-Prieto, Coral, Gabriel, Richard, Dehio, Christoph, Schmidt, Manfred, Llosa, Matxalen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452801/
https://ncbi.nlm.nih.gov/pubmed/28411218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00207-17
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